Full Spectrum oil would be the most “beneficial” for attaining whatever the desired effect. This is because it resembles the whole plant most closely (not including hemp seed oil), and it needing the least amount of processing. CBD isolate is just a piece to the puzzle, but extremely useful for many applications needing an odorless, tasteless, miscible alternative to the raw nature of full spectrum oil. For drug testing, odor, taste or mixing purposes – use Isolate. everything else – Full Spectrum.